Patterns of CSF and neuroimaging biomarkers in Alzheimer's Disease and mild cognitive impairment Lead Investigator: Xiaolei Shi Institution : Sun Yat-sen University E-Mail : shixlei@mail2.sysu.edu.cn Proposal ID : 1461 Proposal Description: We aimed to use this database to study the patterns of CSF biomarkers (A??42, tau) and neuroimaging markers for cerebral small vessel pathology (white matter hyperintensity, perivascular spaces and the like) among AD and MCI. Their associations with cognitive progression and reversion will also be studied. This will help understand the potential mechanisms of them